Course Description:
The online molecular diagnostics course (CLSC 5112)
is a 3 credit academic credit course that provides foundation knowledge
in
molecular biology, genetics, and the molecular basis of selected human
diseases. An in-depth review of the theory of molecular techniques such
as
nucleic acid hybridization, amplification, sequencing, and genotyping
is
covered. In addition, the application of these techniques in the
diagnosis,
monitoring, therapeutic decision-making, and prediction of genetic, hematopathological, infectious, and malignant
diseases at
the nucleic acid level is discussed. Additional topics include pharmacogenetics, laboratory practices and
ethical
issues.
Course Dates: Sept. 8, 2009 - Dec. 18, 2009.
Prerequisites:
Baccalaureate
degree with coursework in biological
sciences and chemistry; previous coursework in molecular biology
recommended,
but not required.
Topics:
Human
Genome & Nucleic Acid Chemistry, Structure & Function
Nucleic
Acid Procedures
Target
Amplification - Polymerase Chain Reaction
Other
Amplification Techniques; Sequencing; Microarrays
Molecular
Techniques in Infectious Diseases
Introduction
to Molecular Genetics
Introduction
to Molecular Oncology
Molecular
Diagnostics in Hematopathology & hereditary Thrombophilias
Pharmacogenetics
Laboratory
Practices
Ethical, legal, Social, and Economic Considerations
Faculty:
Helen
Fernandes, PhD, DABCC
Associate Professor
Director of Molecular Diagnostics
Department of Pathology and Laboratory Medicine
UMDNJ-NJ Medical School, Newark, NJ
Elaine
M. Keohane, PhD, CLS(NCA),CLSp(MB)
Professor, Dept of Clinical Laboratory Sciences
UMDNJ-School of Health Related Professions, Newark, NJ
Shashi Mehta, PhD
Associate Professor, Dept of Clinical Laboratory Sciences
UMDNJ-School of Health Related Professions, Newark, NJ
Anjali Seth, PhD, CLSpMB(NCA)
Supervisor, Molecular Diagnostics Laboratory
Department of Pathology and Laboratory Medicine
UMDNJ-NJ Medical School, Newark, NJ
Gregory
Tsongalis, PhD,
H.C.L.D., F.A.C.B.
Director of
Molecular Pathology
Associate Director, of Clinical Chemistry
Hartford Pathology Associates and the
Department of Pathology and Laboratory Medicine
Hartford Hospital, Connecticut
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